Uniek schreef op 3 oktober 2020 12:45:
[...]
Building on our solid foundation, which we established
through the success of RUCONEST®/rhC1INH, was our
focus throughout the year. Our increased sales level
has driven the need for significant further expansion of
our raw materials production capacity, and as such we
have now initiated a second and third facility expansion
If successful in our new indications, we would require
much larger volumes of rhC1INH than is possible using
our current set-up and we are therefore making the
necessary preparations. To this extent we are working
towards producing rhC1INH from our cattle lines.
Finally, in order to upscale the production process,
we are investing in our own downstream processing
(DSP) plant, to enable extra capacity for the purification
process of the proteins from the raw material milk to
be brought in-house. The first facility, together with
improvements being made in the process in association
with our manufacturing partner Sanofi, will more than
double our current capacity. Once we have successfully
integrated one DSP plant, and if we obtain positive data
from either of our current clinical studies, we can start to
add additional facilities to increase capacity further as
necessary. In the mean time, having our own DSP plant
allows us to lower our cost of goods materially ahead of
any such new applications for the product.
btw het was Regeneron en Sanofi trump .....speelt er iets achter de schermen, dat Sanofi heeft gezegd tegen Regeneron over Pharm/Ruc - Interleukin-6 (IL-6) en u misschien een Combo / cocktail ???